Django deployment with uWSGI and NGinx: No Apache required!
uWSGI is a fast, clusterable WSGI server.
I've got nothing against Slicehost, but after buying the latest appsumo.com bundle, which included a $60 credit with Linode, I decided to make the switch. After all, I get twice the RAM with Linode for the same price, and the ping times are already substantially faster.
For no particular reason, I decided to try uWSGI instead of mod_wsgi this time. uWSGI has modules available for many servers, apache and nginx included. You run the uwsgi process (or a cluster thereof), tell nginx to hook up to it/them, and your app is served. It reminds me a bit of mongrel with Apache, although that's probably totally wrong.
A chap named Simon Westphahl wrote a very nice post on deploying Django on nginx and uwsgi. I recommend you read it if you're looking to set something up.
I wrote this post with the intention of describing some caveats to the article linked above, but that was a month ago, so I don't remember them. Ah well. I guess I'll just post a blanket recommendation to try uWSGI. It is presently serving viclistings.com much faster than my (probably misconfigured) Apache + mod_wsgi setup.